Definitions

1. Chloramphenicol is an antibiotic and works by killing or slowing the growth of sensitive bacteria in the body.
2. Chloramphenicol is a rare example of a naturally occurring nitro compound. (Web site)
3. Chloramphenicol (INN) is a bacteriocidal antimicrobial.
4. Chloramphenicol is a broad spectrum antibiotic, but again it is not usually effective against Pseudomonas. (Web site)
5. Chloramphenicol was the first antibiotic successfully used to treat Salmonella food poisoning. (Web site)

Potentially Dangerous Agents

1. Chloramphenicol must not be used when less potentially dangerous agents will be effective.

Chloramphenicol Palmitate Ester

1. In some countries, chloramphenicol is sold as chloramphenicol palmitate ester. (Web site)

Chloramphenicol Acetyl Transferase

1. CAT stands for chloramphenicol acetyl transferase, a bacterial enzyme which inactivates chloramphenicol by acetylating it. (Web site)

Chloramphenicol Acetyltransferase

1. Chloramphenicol acetyltransferase is a bacterial enzyme that detoxifies the antibiotic chloramphenicol. (Web site)

Kidneys

1. Only a tiny fraction of the chloramphenicol is excreted by the kidneys unchanged. (Web site)
2. The majority of the chloramphenicol dose is excreted by the kidneys as the inactive metabolite, chloramphenicol glucuronate. (Web site)

Water

1. The intravenous (IV) preparation of chloramphenicol is the succinate ester, because pure chloramphenicol does not dissolve in water. (Web site)

Production

1. This reaction is used in the production of various antibiotics including chloramphenicol, dihydrostreptomycin, and thiophenicol. (Web site)

Enzyme

1. In resistant gram-negative bacteria, chloramphenicol acetyltransferase is a constitutive enzyme; in gram-positive organisms, the enzyme is inducible.

Inactive

1. Chloramphenicol palmitate ester is inactive, and is hydrolysed to active chloramphenicol in the small intestine. (Web site)

Isolation

1. Isolation of chloramphenicol-resistant Salmonella was correlated with chloramphenicol use on the farms (24). (Web site)

Toxicity

1. Because of its toxicity, chloramphenicol is rarely prescribed for infections that can be treated by other antibiotics. (Web site)

Impairment

1. In liver impairment, the dose of chloramphenicol must therefore be reduced. (Web site)

Seven Patients

1. Administration of chloramphenicol to the seven patients reduced 14CO2 specific activity significantly.

Strains

1. The chloramphenicol acetyltransferase activity in all of the strains is chloramphenicol inducible. (Web site)

Plasmid

1. Chloramphenicol and sulphonamide resistances were determined by one plasmid, of IncH, whose carriage also changed the Vi phage type. (Web site)

Certain Medications

1. Inherited or acquired after excessive alcohol use, certain medications, chloramphenicol, cancers, rheumatoid arthritis, more common in elderly 55. (Web site)

Medicines

1. Some medicines, such as diuretics and chloramphenicol, can slow the production of platelets. (Web site)
2. Chloramphenicol belongs to the family of medicines called antibiotics. (Web site)

Chemotherapy Drugs

1. High blood pressure tests drugs that can decrease the rbc count include: chemotherapy drugs; chloramphenicol.

Dairy Farms

1. Isolation of chloramphenicol-resistant salmonella from dairy farms was associated with the use of chloramphenicol at those dairies. (Web site)

Aplastic Anaemia

1. In the West, chloramphenicol is mostly restricted to topical uses because of the worries about the risk of aplastic anaemia. (Web site)

Substrate Binding

1. Chloramphenicol directly interferes with substrate binding, macrolides sterically block the progression of the growing peptide. (Web site)

Bacterial Conjunctivitis

1. In the West, the main use of chloramphenicol is in eye drops or ointment for bacterial conjunctivitis. (Web site)

Therapy

1. Statewide study of chloramphenicol therapy and fatal aplastic anemia.
2. CLAUDON DB, HOLBROOK AA. Fatal aplastic anemia associated with chloramphenicol (chloromycetin) therapy; report of two cases.

Drugs

1. Many drugs can cause acquired red cell aplasia, the most common being chloramphenicol, azathioprine, procainamide, phenytoin, and isoniazid.

Patients

1. Plasma levels of chloramphenicol must be monitored in neonates and in patients with abnormal liver function. (Web site)

Vancomycin

1. These isolates were most sensitive to meropenem, amikacin, vancomycin, chloramphenicol, ciprofloxacine and third generation cephalosporine. (Web site)

Penicillins

1. Pasteurella are generally susceptble to chloramphenicol, the penicillins, and tetracycline. (Web site)

Penicillin

1. Metronidazole Injection, USP RTU® is effective in Bacteroides fragilis infections resistant to clindamycin, chloramphenicol and penicillin. (Web site)

Resistance

1. Chloramphenicol resistance may be carried on a plasmid that also codes for resistance to other drugs. (Web site)

Treatment

1. The most serious side effect of chloramphenicol treatment is aplastic anaemia.
2. In the West, chloramphenicol is still widely used in topical preparations (ointments and eye drops) for the treatment of bacterial conjunctivitis. (Web site)
3. It is common for chloramphenicol to cause bone marrow suppression during treatment: this is a direct toxic effect of the drug on human mitochondria. (Web site)

Aplastic Anemia

1. Benzene-based compounds, airplane glue, and drugs such as chloramphenicol have been linked to aplastic anemia.
2. In addition, there have been reports of aplastic anemia attributed to chloramphenicol which later terminated in leukemia. (Web site)
3. A fatal case of aplastic anemia following chloramphenicol (chloromycetin) therapy.

Resistant

1. All Bifidobacterium and Lactobacillus strains were sensitive to chloramphenicol and imipenem and most of the strains were resistant to metronidazole.
2. Some strains are also found to be resistant to one of the following: cephalosporins, Bactrim, chloramphenicol, or a macrolide.
3. Salmonella heidelberg was isolated from each, and in all cases was resistant to chloramphenicol, sulfamethoxazole, and tetracycline.

Antibiotic

1. Paraxin (Chloramphenicol) An antibiotic used to treat a variety of bacterial infections.
2. The antibiotic, chloramphenicol and the anti-inflammatory, phenylbutazone are two examples. (Web site)

Antibiotics

1. Protein translation is interrupted by antibiotics such as tetracycline or chloramphenicol that interfere with protein synthesis. (Web site)
2. Acinetobacter species are innately resistant to many classes of antibiotics, including penicillin, chloramphenicol, and often aminoglycosides. (Web site)
3. While chloramphenicol and the macrolide class of antibiotics both interact with the 50S ribosomal subunit, chloramphenicol is not a macrolide. (Web site)

Gentamicin

1. Antibiotics such as gentamicin, clindamycin, or chloramphenicol are used to treat infection. (Web site)
2. Other antibiotics, such as chloramphenicol, Baytril, gentamicin, or sulfa drugs such as DiTrim are of no use in this condition. (Web site)

Erythromycin

1. Antagonism has been demonstrated in vitro between erythromycin and clindamycin, lincomycin, and chloramphenicol.
2. Children are more likely than adults to be infected with strains resistant to chloramphenicol, erythromycin, or Bactrim.

Ampicillin

1. Typhi strains that confer resistance to chloramphenicol, trimethoprim, and ampicillin, quinolones have become the primary drugs for treatment (1). (Web site)
2. Ampicillin, chloramphenicol, and TMP-SMX were considered standard agents for the treatment of Salmonella infections.
3. Most Salmonella Typhimurium isolates showed resistance to ampicillin, chloramphenicol, dihydrostreptomycin and oxytetracycline. (Web site)

Sulfonamides

1. Thus, chloramphenicol may produce pancytopenia, whereas a granulocytopenia is more frequently observed with toxicity to sulfonamides or antithyroid drugs.
2. Other drugs that significantly increase PHT levels are isoniazid, cimetidine, chloramphenicol, dicumarol, and sulfonamides.

Tetracyclines

1. Penicillins, tetracyclines, chloramphenicol, and erythromycin can be given to treat leptospirosis.
2. Shigella is usually also resistant to metronidazole, streptomycin, tetracyclines, chloramphenicol and sulphonamides.

Tetracycline

1. Erythromycin (Maracyn), nitrofurazone, nifurpirinol, acriflavine, chloramphenicol or tetracycline can be used to treat the columnaris itself. (Web site)
2. Observed resistant patterns of R plasmids were mainly multiple and encoded to resistance to tetracycline, chloramphenicol, streptomycin and sulfisoxazole.
3. In more severe infections, antibiotics such as tetracycline and chloramphenicol may be necessary. (Web site)

Chloramphenicol

1. These salmonellae are resistant to ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline.
2. Antibiotics that should be avoided in treatment of liver disease include chloramphenicol, lincomycin, sulfonamides, erythromycin, and hetacillin. (Web site)
3. Usually sensitive to gentamicin, tetracycline, and chloramphenicol; usually resistant to ampicillin and cephalosporins Genus Plesiomonas i.

Categories

1. Tetracycline
2. Sulfonamides
3. Ampicillin
4. Erythromycin
5. Gentamicin
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