Severe Pancytopenia

1. Monosomy 7 generally occurred in those with a minimal clinical response or in those who relapsed with severe pancytopenia.

Syndrome

1. Only patients with a diagnosis of JMML fitted what has previously been referred to as the monosomy 7 syndrome. (Web site)

Chromosome

1. Outcome of patients with deletion 5q or with loss of chromosome 5 (monosomy 5) was analyzed. (Web site)

Clone

1. Immunosuppressive therapy was effective along with the disappearance of monosomy 7 clone. (Web site)

Children Younger

1. A subgroup of children younger than 4 years at diagnosis with myelodysplasia have monosomy 7.

Cases

1. However, it seems controversial recently, because some cases of monosomy 7 syndrome showed spontaneous remission.
2. Monosomy of chromosome 9 and gain of a copy of chromosome X (in both sexes) were observed in 100% of cases.

Thirteen Patients

1. Thirteen patients showed evolution to other hematologic diseases, including monosomy 7. (Web site)

Myelodysplastic Syndrome

1. Preferential cytogenetic response to continuous intravenous low-dose decitabine (DAC) administration in myelodysplastic syndrome with monosomy 7. (Web site)

Aneuploidy

1. Monosomy, or the loss of one chromosome from each cell, is another kind of aneuploidy.

Patients

1. Monosomy 7 in patients with aplastic anemia and paroxysmal nocturnal hemoglobinuria with evolution into acute myeloid leukemia. (Web site)
2. In addition, patients often have an elevated hemoglobin F, hypersensitivity of the leukemic cells to granulocyte colony-stimulating factor, and monosomy 7.
3. In bone marrow CD34 cells of patients with myelodysplastic syndrome and monosomy 7, GCSF receptor (GCSFR) protein was increased. (Web site)

Turner Syndrome

1. Turner syndrome encompasses several chromosomal abnormalities, of which monosomy X, is the most common. (Web site)

Trisomy

1. One extra copy of a chromosome is called a trisomy, while one missing copy of a chromosome is called a monosomy. (Web site)

Trisomy 21

1. In total, 30 had monosomy 7 and four had trisomy 8, one of whom also had trisomy 21. (Web site)
2. The myelodysplastic syndrome and AML may also show acquired monosomy 7, trisomy 21, and ras mutations (11).
3. Leukemia in SCN may also show acquired monosomy 7, trisomy 21, and ras mutations.

G-Csf

1. The significance of monosomy 7 and trisomy 21 in KD treated with G-CSF is discussed. (Web site)

Granulocyte Colony-Stimulating Factor

1. The evidence of clonal evolution with monosomy 7 in aplastic anemia following granulocyte colony-stimulating factor using the polymerase chain reaction. (Web site)

Monosomy

1. Long-term administration of G-CSF for aplastic anemia is closely related to the early evolution of monosomy 7 MDS in adults. (Web site)
2. Long-term administration of G-CSF for aplastic anaemia is closely related to the early evolution of monosomy 7 MDS in adults. (Web site)
3. MDS. Stereotypical patterns of aneuploidy develop in a minority of patients over time: monosomy 7 or trisomy 8 is most characteristic. (Web site)

Categories

1. Long-Term Administration
2. Granulocyte Colony-Stimulating Factor
3. Trisomy 21
4. Health > Diseases > Genetic Disorders > Turner Syndrome
5. Aneuploidy
6. Books about "Monosomy" in Amazon.com
   

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