Definitions

1. IgE is a cytophilic molecule whose Fc fragment (stem of the Y) is affixed to mast cells and basophils (IgE levels in the blood serum are low).
2. IgE is secreted by plasma cells and attaches itself to basophils and mast cells.
3. IgE is important in the release of pharmacologically active agents from mast cells and thus causes asthma and hayfever.
4. If IgE is present in your lung tissue, it frequently causes symptoms such as shortness of breath or asthma.
5. Total IgE was significantly higher in the ABPA group (P<0.01).

Idiopathic Generalized Epilepsy

1. Idiopathic Generalized Epilepsy (IGE) in our study commonly presented with both sleep and wake seizures although wake seizures were more likely.

Ige Binding Epitopes

1. Thus, it was found that both IgG and IgE binding epitopes on shrimp tropomyosin are identical.

Specific Ige Antibody

1. Each allergen has a specific IgE antibody.

Ige Antibodies Present

1. The quantity of IgE antibodies present determines the strength of your allergic reaction.

Igg Antibodies

1. Human response to fungal antigens may induce IgE or IgG antibodies that connote prior exposure but not necessarily a symptomatic state.

Ige Reactivity

1. IgE reactivity against a cross-reactive allergen in crustacea and mollusca: evidence for tropomyosin as the common allergen.
2. The highest frequencies of IgE reactivity to food were found in the group of children sensitized to the combination of birch, timothy and mugwort pollen.

Rast

1. RAST, RadioAllergoSorbent Test, is used to detect IgE antibodies present to a certain allergen.

Allergen-Specific Ige

1. RAST measures allergen-specific IgE. Compared to skin tests, RAST has the disadvantage of limited allergen selection and reduced sensitivity.

Specific Ige

1. When the allergen next encounters its specific IgE, it attaches to the antibody like a key fitting into a lock.
2. Once the specific IgE has formed, subsequent exposure to the fungus can result in an allergic reaction.

Ige Antibody

1. The disorder is not associated with IgE antibody (but a small subset of patients may eventually establish IgE antibody responses).

Present

1. Although such a reaction indicates that IgE antibody to a specific allergen is present, respiratory symptoms do not necessarily result.

Person

1. Three skin tests determine if a person has IgE to specific allergens.

Blood Cells

1. During this process, the body's white blood cells develop immunoglobulin E (IgE) antibodies to the semen allergens.

Measurement

1. Marley, SE, Lammie, PJ, Eberhard, ML. Immunopurification and measurement of IgE in serum samples from bancroftian filariasis patients.
2. Blood samples were drawn for measurement of specific IgE, IgG 4, and serum cytokines before and after treatment.

Inflammation

1. IgE antibody mediated inflammation of rat lung: histologic and bronchoalveolar lavage assessment.

Individual

1. Total and allergen specific IgE was measured in every individual.

Ige Antibodies

1. For example, the RAST (RadioAllergoSorbent Test) detects the presence of IgE antibodies to a particular allergen.
2. If the patient has a high level of IgE antibodies in the tissue, he or she will develop what is called a "wheal and flare" reaction in about 15-20 minutes.
3. IgE antibodies against bovine serum albumin in a case of eosinophilic gastroenteritis.

Children

1. Dill I, Niggemann B. Domestic fungal viable propagules and sensitization in children with IgE mediated allergic diseases.
2. The mechanism and significance of elevated serum IgE levels remain unclear in children with HIV, and warrant further investigation.

Positive

1. IgE or IgG antibodies used as exposure markers, were positive in about less than 25% of all cases.
2. Frequently IgE "RAST" positive and skin test positive.

Monoclonal Antibody

1. A monoclonal antibody, omalizumab works by blocking immunoglobulin E (IgE), an antibody produced in excessive amounts in people suffering from hay fever.

Body

1. When an allergen enters the body, the immune system produces IgE antibodies.

Symptoms

1. Skin tests, although fairly reliable for the detection of IgE to environmental allergens, are not well correlated with food allergy signs and symptoms.

Allergic Rhinitis

1. This syndrome should be distinguished from allergic rhinitis, a syndrome that immunoglobulin E (IgE) is thought to mediate.

Diagnosis

1. The most valid parameters for the diagnosis of ABPA in CF are SPT to Af., IgE to Af.

Blood Tests

1. Blood tests for IgE may be less accurate than skin tests.

Exposure

1. After exposure to an allergen, some people make IgE antibodies as well as B and T memory cells.

Chartarum

1. The IgE antibodies to S. Chartarum suggests that this fungus may be a cause of allergic reaction.
2. Using enzyme immunoassay 65 of 132 samples tested contained IgG antibodies to S. chartarum and 13 of 139 samples contained IgE antibodies to S. chartarum.

Reactions

1. Most reactions to processed free glutamic acid (MSG), as contained in gelatin, are not IgE mediated.

Allergic Reactions

1. Some people have allergic reactions where IgE is not involved.
2. IgE refers to a class of antibodies in blood plasma that activate allergic reactions to foreign particles.

Asthma

1. Long-term acquisition of allergen-specific IgE and asthma following allogeneic bone marrow transplantation from allergic donors.

Atopic Dermatitis

1. IgE (immunoglobulin E) controls the immune system's allergic response and is often high in atopic dermatitis.
2. Recombinant gamma interferon in treatment of patients with atopic dermatitis and elevated IgE levels.
3. Personality characteristics and serum IgE level in patients with atopic dermatitis.

Proteins

1. The proteins are responsible for allergic sensitization predisposing to IgE mediated reactions.
2. The IgE antibodies identify the allergenic proteins as harmful and initiate the allergic reaction.

Blood Serum

1. Moreover, the appearance of the specific IgE antibodies against common allergens in blood serum was tested in children at the age of 6.
2. In addition to a general physical examination, the doctor may order a blood test to look for the presence of elevated IgE levels in the blood serum.

Antibody

1. Diagnostic tests can be done by using a blood sample from a patient to detect the levels of IgE antibody to a particular allergen.
2. These substances interact with IgE antibody on the mast cells inside the nose.
3. Primed for action, the IgE antibody now only have to patiently wait for re-exposure to food allergens.

Response

1. A very common allergen with an IgE mediated response.
2. These health outcomes are mainly due to high molecular weight proteins in seafood causing an IgE mediated response.
3. In allergic diseases, IgE antibodies are produced in response to different allergens.

Food Allergy

1. IgE to food allergens are highly prevalent in patients allergic to pollens, with and without symptoms of food allergy.
2. Another type of food allergy is called Gastrointestinal Food Hypersensitivity.[7] It can be IgE or Non-IgE mediated.

Food

1. Not all adverse reactions to food are IgE mediated, and most cases of IgE-mediated food allergy do not have eosinophilic gastroenteritis.
2. If the scratch test is positive, the patient has IgE on the skin's mast cells that is specific to the food being tested.
3. As this food is digested, it triggers certain cells to produce specific IgE in large amounts.

Levels

1. The increase in the IgE levels, however, cannot be associated with severity of the chronic liver disease.
2. One called the radioallergosorbent Test (RAST) is used to detect increased levels of allergen-specific IgE in response to particular allergens.
3. Even the levels the amount of IgE specific to certain allergens can be measured through use of the radioallergosorbent test (RAST).

Blood

1. The high levels of IgE in the blood of AD patients are produced by hyperactive T helper 2 cells reacting against antigens in the environment.
2. About 80 to 90 percent of children with AD also have unusually high levels of an antibody called IgE in their blood.
3. Blood test - the test simply measures the level of IgE antibody in the blood.

Elevated

1. At age 7, his total IgE was highly elevated, and specific IgE was strongly positive to egg yolk, crab, and shrimp [ 20].
2. The erythrocyte sedimentation rate (ESR) and serum IgE level can be elevated.

Eosinophilia

1. Allergic eosinophilic gastroenteritis is characterized by elevated total IgE, specific IgE to food antigens, and eosinophilia of tissue and blood.

Eosinophils

1. Chronic infection with Schistosoma mansoni induces in humans and mice a Th2-dominant immune response in which eosinophils and IgE are conspicuously elevated.

Allergy

1. Double blind, placebo controlled food reactions do not correlate to IgE allergy in the diagnosis of staple food related gastrointestinal symptoms.
2. The higher the radioactivity, the higher the level of IgE in the blood and the more severe the allergy.
3. IgE-mediated allergy is the allergy that happens when IgE antibody (one type of the white blood cell) binds with the mast cell.

Allergies

1. Eosinophils - These white blood cells are elevated in IgE mediated allergies, the presence of parasites, and food sensitivities.
2. IgE levels are often higher in people who have allergies or asthma.

Allergic

1. Positive results simply indicate that the individual has IgE (allergic) antibodies to the substance tested.
2. Non-allergic rhinitis: This form of rhinitis does not depend on the presence of IgE and is not due to an allergic reaction.
3. Before an allergic reaction can occur, a person who is predisposed to form IgE to foods first has to be exposed to the food.

Histamine

1. They bind IgE, supply the histamine and heparin response that gives you a healing inflammation, and cause allergies.
2. The presence in serum of IgE specific to moulds was verified by histamine release test (HRT) based on passive sensitization of basophil leukocytes.
3. It also causes hypoglycemia, increased IgE synthesis, and increased histamine and endotoxin sensitivity.

Categories

1. Allergen
2. Mast Cells
3. Igg
4. Biochemistry > Molecular Biology > Proteins > Antibodies
5. Basophils

Related Keywords

* Allergen * Allergens * Antibodies * Basophils * Igg * Immunoglobulin * Mast Cells

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